Cystic Fibrosis:
2800 articles, I have seen some and I commented in this post ....
Cystic fibrosis is an autosomal recessive disease reported in 1 in 2500 live births in North America and Northern European Caucasians. Classic is the chronic bacterial infection of the respiratory tract and sinuses, malabsorption of fat, infertility in men, and high concentrations of chloride in sweat. Less well-recognized findings associated with cystic fibrosis were cutaneous, which can be primary or secondary manifestations of the disease. Patients demonstrate more atopic and drug hypersensitivity reactions than the general population, but have similar rates of urticaria compared with the general population. In atypical presentations of cystic fibrosis, the nutrient deficiency dermatitis of the disease, may help with diagnosis and, in particular, may be the presenting sign. Other dermatologic manifestations CF aquagenic include premature skin wrinkling and cutaneous vasculitis, which can be associated with arthralgias. Familiarity with the nutrient deficiency dermatitis of this entity may play a role in early diagnosis of the disease, and other skin findings add to our understanding of the nature of its protean manifestations.
(200 words approx)
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